In 1932, in Boston, the tough Harvard graduated Dr. Meg Laurel lashes out at the corrupt and powerful Judge Adamson. Her husband Dr. Thom Laurel is worried with the damage that the judge may cause in his career and Meg decides to leave him in Boston and return to the orphanage where she was raised to visit her friend Effie Webb. She learns that the orphanage is closed and Effie has returned to her hometown Eagle's Nest in the mountain. When Dr. Laurel arrives at Effie's home, she finds that her friend is on her deathbed under the care of the healer Granny Arrowroot. Dr. Laurel is unsuccessful in her attempt to save Effie that asks her to stay to help her people with her medical knowledge. Soon Dr. Laurel finds an illiterate and backward people that appraises traditions and belief more than the modern medical techniques. Further, she goes against Granny and is not accepted by the community. But both Meg and Granny discover that they have much to learn with each other.